Calix(4)pyrrole

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Calix(4)pyrrole is a type of macrocycle that is used in the field of supramolecular chemistry. It is a heterocyclic compound that is composed of four pyrrole units linked together by methine bridges.

Structure and Synthesis[edit | edit source]

The structure of calix(4)pyrrole is characterized by a central cavity that is capable of binding anions. This property makes it useful in the field of anion recognition. The synthesis of calix(4)pyrrole involves the condensation of pyrrole and ketones in the presence of an acid catalyst.

Applications[edit | edit source]

Calix(4)pyrrole has been used in a variety of applications in supramolecular chemistry. It has been used as a receptor for anions, as a sensor for anions, and as a building block for the construction of larger supramolecular structures. It has also been used in the development of new materials and in the study of anion-π interactions.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD