Canine discoid lupus erythematosus

Canine discoid lupus 3

Canine discoid lupus erythematosus (CDLE) is a chronic autoimmune disease that affects the skin of dogs. It is a form of lupus erythematosus, specifically affecting the epidermis and causing dermatological symptoms. CDLE is one of the most common autoimmune skin diseases in dogs.

Symptoms

The primary symptoms of CDLE include:

• Erythema (redness of the skin)
• Scaling and crusting of the skin
• Depigmentation (loss of skin color)
• Alopecia (hair loss)
• Ulceration and scarring

These symptoms are most commonly observed on the nose, face, ears, and occasionally on the paws and other parts of the body. The condition can worsen with exposure to ultraviolet light.

Diagnosis

Diagnosis of CDLE is typically based on:

• Clinical signs and symptoms
• Skin biopsy and histopathological examination
• Immunofluorescence testing

Differential diagnosis should rule out other conditions such as pemphigus foliaceus, dermatophytosis, and bacterial pyoderma.

Treatment

Treatment options for CDLE include:

• Topical and systemic corticosteroids
• Immunosuppressive drugs such as cyclosporine
• Antimalarial drugs like hydroxychloroquine
• Vitamin E and essential fatty acids supplements
• Avoidance of sunlight and use of sunscreen on affected areas

Prognosis

The prognosis for dogs with CDLE varies. While the condition is chronic and can be managed with treatment, it may require lifelong therapy and regular monitoring by a veterinarian.

See also

• Lupus erythematosus
• Autoimmune disease
• Dermatology
• Veterinary medicine