Cefovecin sodium

Cefovecin sodium is a broad-spectrum antibiotic belonging to the cephalosporin class. It is primarily used in veterinary medicine to treat bacterial infections in dogs and cats. Cefovecin sodium is known for its long-acting properties, allowing for less frequent dosing compared to other antibiotics.

Mechanism of Action

Cefovecin sodium works by inhibiting the synthesis of the bacterial cell wall. It binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which leads to the interruption of cell wall synthesis and ultimately causes bacterial cell death. This mechanism is similar to other beta-lactam antibiotics.

Pharmacokinetics

Cefovecin sodium is administered via subcutaneous injection. It has a long half-life, which allows it to remain active in the body for an extended period. This long duration of action is particularly beneficial in veterinary medicine, as it reduces the need for frequent dosing and improves compliance.

Indications

Cefovecin sodium is indicated for the treatment of various bacterial infections in dogs and cats, including:

• Skin infections
• Soft tissue infections
• Urinary tract infections
• Periodontal disease

Side Effects

Common side effects of cefovecin sodium may include:

• Vomiting
• Diarrhea
• Lethargy
• Anorexia

In rare cases, allergic reactions may occur. It is important to monitor animals for any signs of adverse reactions following administration.

Contraindications

Cefovecin sodium should not be used in animals with a known allergy to cephalosporins or other beta-lactam antibiotics. Caution is advised when using this medication in animals with a history of kidney disease or other serious health conditions.

Related Pages

• Antibiotic
• Cephalosporin
• Veterinary medicine
• Bacterial infection
• Beta-lactam antibiotic