Ceftezol
Ceftezol is a cephalosporin antibiotic used to treat a variety of bacterial infections. It belongs to the first generation of cephalosporins and is known for its effectiveness against Gram-positive bacteria.
Mechanism of Action[edit | edit source]
Ceftezol works by inhibiting the synthesis of the bacterial cell wall. It binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which leads to the interruption of cell wall synthesis and ultimately causes bacterial cell death.
Pharmacokinetics[edit | edit source]
Ceftezol is administered via intravenous or intramuscular injection. It is well-absorbed and distributed throughout the body, reaching therapeutic concentrations in various tissues and fluids. The drug is primarily excreted unchanged in the urine.
Clinical Uses[edit | edit source]
Ceftezol is used to treat infections caused by susceptible strains of bacteria, including:
- Respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Bone and joint infections
- Septicemia
Side Effects[edit | edit source]
Common side effects of Ceftezol include:
Contraindications[edit | edit source]
Ceftezol should not be used in patients with a known allergy to cephalosporins or any component of the formulation. Caution is advised in patients with a history of penicillin allergy due to potential cross-reactivity.
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Contributors: Prab R. Tumpati, MD