Cell Migration
Cell Migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations. Errors during this process have serious consequences, including intellectual disability, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling, for example, invasive tumor cells.
Overview[edit | edit source]
Cell migration is a complex process that is vital for the development and survival of multicellular organisms. It is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations.
Mechanism[edit | edit source]
The mechanism of cell migration involves the integration of complex signaling pathways that are responsible for the regulation of cytoskeletal dynamics and the formation of cell-substrate adhesion. These processes are tightly regulated and coordinated to ensure the directional movement of cells.
Role in Disease[edit | edit source]
Errors in cell migration have serious consequences, including intellectual disability, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling, for example, invasive tumor cells.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
