Cervical mucus plug

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An overview of the cervical mucus plug in pregnancy


Cervical Mucus Plug[edit | edit source]

The cervical mucus plug is a collection of cervical mucus that forms in the cervix during pregnancy. It acts as a barrier to protect the uterus from infections and helps maintain a sterile environment for the developing fetus.

Diagram illustrating the position of the cervical mucus plug in the cervix.

Formation[edit | edit source]

The cervical mucus plug forms in the early stages of pregnancy. Increased levels of estrogen and progesterone stimulate the cervical glands to produce mucus, which accumulates and thickens to form the plug. This process typically begins shortly after conception and continues as the pregnancy progresses.

Function[edit | edit source]

The primary function of the cervical mucus plug is to act as a protective barrier. It prevents bacteria and other pathogens from entering the uterine cavity, thereby reducing the risk of infection to the amniotic sac and the fetus. The plug also helps maintain the cervical canal in a closed state, supporting the pregnancy.

Changes During Pregnancy[edit | edit source]

Throughout pregnancy, the cervical mucus plug remains in place, but it may undergo changes in consistency and appearance. As the body prepares for labor, hormonal changes cause the cervix to soften and dilate, leading to the expulsion of the mucus plug. This event is often referred to as "losing the mucus plug" and can occur days or weeks before labor begins.

Clinical Significance[edit | edit source]

The loss of the cervical mucus plug is considered a sign that the body is preparing for labor, but it does not necessarily indicate that labor is imminent. Some women may notice a discharge that is clear, pink, or slightly bloody, known as a "bloody show." However, the timing of labor can vary significantly among individuals.

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Contributors: Prab R. Tumpati, MD