Chlorisondamine

Chlorisondamine is a ganglionic blocker, a type of drug that inhibits the transmission of nerve impulses in the autonomic ganglia. It is used in scientific research to induce hypertension in laboratory animals.

Pharmacology

Chlorisondamine works by blocking the nicotinic acetylcholine receptors (nAChRs) in the autonomic ganglia. These receptors are responsible for transmitting signals from the nervous system to various organs in the body. By blocking these receptors, chlorisondamine disrupts the normal functioning of the autonomic nervous system, leading to a variety of physiological effects.

Uses

In scientific research, chlorisondamine is often used to induce hypertension in laboratory animals. This is done to study the effects of high blood pressure on various bodily systems, and to test the efficacy of antihypertensive drugs.

Side Effects

As a ganglionic blocker, chlorisondamine can cause a variety of side effects, including hypotension, bradycardia, and constipation. These side effects are due to the disruption of normal autonomic nervous system function.

See Also

• Ganglionic blocker
• Nicotinic acetylcholine receptor
• Hypertension

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