Chloroacetamide

Chloroacetamide is an organic compound with the formula ClCH₂CONH₂. This white solid is a widely used preservative and antimicrobial agent that is used in a variety of applications, including cosmetics, shampoo, and skin care products.

Chemical Structure and Properties

Chloroacetamide is a derivative of acetic acid, with a chlorine atom replacing one of the hydrogen atoms on the methyl group, and an amide group replacing the hydroxyl group. This gives it the ability to form hydrogen bonds, which contributes to its antimicrobial properties. It is a white solid at room temperature, with a melting point of 119-121 °C.

Uses

Chloroacetamide is primarily used as a preservative and antimicrobial agent. It is effective against a broad spectrum of microorganisms, including bacteria, yeasts, and molds. This makes it a popular choice for use in personal care products, where it helps to prevent spoilage and extend shelf life.

In addition to its antimicrobial properties, chloroacetamide also has some antioxidant activity. This can help to protect products from oxidation, which can cause changes in color, odor, and texture.

Safety

The safety of chloroacetamide has been extensively studied. It is generally considered safe for use in cosmetics and personal care products at concentrations up to 0.3%. However, it can cause skin irritation and allergic reactions in some individuals, particularly at higher concentrations. For this reason, it is recommended to perform a patch test before using products containing chloroacetamide for the first time.

See Also

• Preservative
• Antimicrobial
• Cosmetics
• Skin care