Chloroprednisone acetate

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Chloroprednisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is used in the treatment of various health conditions that involve inflammation.

Chemistry[edit | edit source]

Chloroprednisone acetate is a synthetic, orally active corticosteroid. It is a chlorine-substituted version of prednisone and an acetate ester of chloroprednisone. The chemical name of chloroprednisone acetate is 21-(Acetyloxy)-9-chloro-17-hydroxy-11,20-dione.

Pharmacology[edit | edit source]

As a glucocorticoid, chloroprednisone acetate has potent anti-inflammatory and immunosuppressive properties. It works by mimicking the effects of cortisol, a hormone naturally produced by the adrenal glands. This leads to a decrease in the immune response and a reduction in inflammation.

Medical uses[edit | edit source]

Chloroprednisone acetate is used to treat a variety of conditions that involve inflammation. These include rheumatoid arthritis, asthma, allergies, and autoimmune diseases. It can also be used to suppress the immune system in patients undergoing organ transplantation.

Side effects[edit | edit source]

Like other corticosteroids, chloroprednisone acetate can have a number of side effects. These can include weight gain, osteoporosis, glaucoma, and Cushing's syndrome. Long-term use can also lead to adrenal insufficiency.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD