Chlorphenesin carbamate
A muscle relaxant used in the treatment of muscle pain and spasms
| Chlorphenesin carbamate | |
|---|---|
|
| |
| Trade names | Maolate
|
| Chemical nomenclature | |
| IUPAC name | 3-(4-Chlorophenoxy)-1,2-propanediol carbamate
|
| Routes | Oral
|
| Legal status | Rx-only |
| Identifiers | |
| CAS Number | 886-74-8 |
| PubChem | 2724 |
| DrugBank | DB04836 |
| ChemSpider | 2622 |
| UNII | 0T493YFU8O |
| KEGG | D07150 |
| ChEMBL | 1201328 |
| Chemical data
| |
| Chemical formula | C10H12N1O4Cl1
|
| SMILES | Clc1ccc(OCC(O)COC(=O)N)cc1
|
Chlorphenesin carbamate is a centrally acting muscle relaxant used to treat muscle pain and spasms. It is a derivative of chlorphenesin, which is primarily used as a preservative in cosmetics. Chlorphenesin carbamate is marketed under the trade name Maolate, among others.
Pharmacology[edit]
Chlorphenesin carbamate works by depressing the central nervous system, leading to muscle relaxation. It is believed to act on the spinal cord and subcortical areas of the brain, reducing muscle hyperactivity and providing relief from muscle spasms.
Medical Uses[edit]
Chlorphenesin carbamate is prescribed for the relief of discomfort associated with acute, painful musculoskeletal conditions. It is often used in conjunction with rest, physical therapy, and other measures to relieve discomfort and improve mobility.
Side Effects[edit]
Common side effects of chlorphenesin carbamate include drowsiness, dizziness, and headache. Less common side effects may include nausea, vomiting, and allergic reactions. Due to its sedative effects, patients are advised to avoid operating heavy machinery or driving while taking this medication.
Contraindications[edit]
Chlorphenesin carbamate is contraindicated in patients with known hypersensitivity to the drug or its components. It should be used with caution in patients with impaired liver or kidney function.
Interactions[edit]
Chlorphenesin carbamate may interact with other central nervous system depressants, such as alcohol, benzodiazepines, and opioids, potentially enhancing their sedative effects. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions.
History[edit]
Chlorphenesin carbamate was first introduced in the 1950s as a muscle relaxant. It has been used in various countries, although its use has declined with the introduction of newer muscle relaxants with more favorable side effect profiles.
Also see[edit]
References[edit]
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