Chronic progressive lymphedema

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Lymphœdème chronique progressif chez un étalon breton de 12 ans (2)

== Chronic Progressive Lymphedema ==

Chronic Progressive Lymphedema (CPL) is a medical condition characterized by the gradual and persistent swelling of tissues due to the accumulation of lymphatic fluid. This condition primarily affects the limbs but can also impact other parts of the body. CPL is a progressive disorder, meaning it worsens over time if left untreated.

Pathophysiology[edit | edit source]

The underlying cause of CPL is the dysfunction of the lymphatic system, which is responsible for the transport of lymph fluid throughout the body. When the lymphatic vessels are damaged or obstructed, lymph fluid accumulates in the tissues, leading to swelling and other complications. This can result from genetic factors, infections, trauma, or other medical conditions.

Symptoms[edit | edit source]

The symptoms of CPL include:

  • Persistent swelling, usually in the limbs
  • Skin changes, such as thickening and hardening
  • Discomfort or pain in the affected area
  • Reduced mobility and flexibility
  • Increased risk of infections, such as cellulitis

Diagnosis[edit | edit source]

Diagnosis of CPL typically involves a combination of medical history, physical examination, and diagnostic tests. These may include:

  • Lymphoscintigraphy: A specialized imaging technique to visualize the lymphatic system
  • Ultrasound: To assess the extent of swelling and rule out other conditions
  • MRI or CT scan: To provide detailed images of the affected tissues

Treatment[edit | edit source]

While there is no cure for CPL, various treatments can help manage the symptoms and slow the progression of the disease. These treatments include:

In severe cases, surgical interventions such as lymphatic bypass surgery or liposuction may be considered.

Prognosis[edit | edit source]

The prognosis for individuals with CPL varies depending on the severity of the condition and the effectiveness of the treatment. Early diagnosis and consistent management can significantly improve the quality of life for those affected.

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Contributors: Prab R. Tumpati, MD