Ciclopirox olamine

Ciclopirox olamine - the olamine salt form of ciclopirox, a synthetic, broad spectrum antifungal agent with additional antibacterial and anti inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as fe3+ and al3+, thereby inhibiting the availability of essential co factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti inflammatory activity by inhibiting 5 lipoxygenase and cyclooxygenase (cox).

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