Cis-4-methylaminorex

Cis-4-Methylaminorex (4-MAR) is a psychoactive drug and stimulant that was first synthesized in the late 20th century. It is a member of the aminorex class of compounds, which are known for their psychostimulant and anorectic properties. Cis-4-Methylaminorex exists as one of the stereoisomers of the 4-Methylaminorex compound, with the cis configuration indicating the specific spatial arrangement of its molecular structure.

Chemistry

Cis-4-Methylaminorex (IUPAC name: (±)-cis-4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine) is a synthetic molecule of the oxazoline family. Its structure is characterized by a core oxazoline ring, a methyl group attached to the 4-position of the ring, and a phenyl group at the 5-position. The cis configuration refers to the orientation of these groups in the three-dimensional space, which significantly affects the compound's biological activity.

Pharmacology

The pharmacological action of cis-4-Methylaminorex is primarily as a central nervous system stimulant. It functions by increasing the release of neurotransmitters such as dopamine and norepinephrine in the brain, leading to stimulant effects. This includes increased alertness, euphoria, and energy, as well as potential appetite suppression. The exact mechanism of action is similar to other stimulants like amphetamine and methamphetamine, but with distinct pharmacokinetic and pharmacodynamic profiles.

Effects

The effects of cis-4-Methylaminorex can vary depending on the dose, route of administration, and individual user characteristics. Commonly reported effects include:

• Increased energy and alertness
• Euphoria
• Decreased appetite
• Increased heart rate and blood pressure
• Potential for psychological dependence

Due to its potent stimulant effects, there is a risk of adverse effects, particularly at high doses or with prolonged use. These can include:

• Anxiety and paranoia
• Insomnia
• Cardiac issues
• Neurotoxicity

Legal Status

The legal status of cis-4-Methylaminorex varies by country, but it has been controlled or banned in many jurisdictions due to concerns over its potential for abuse and harm. In some places, it is classified as a Schedule I or equivalent substance, indicating a high potential for abuse with no accepted medical use.

See Also

• Aminorex
• Stimulant
• Psychoactive drug
• Neurotransmitter