Clopidol

From WikiMD's Wellnesspedia

Clopidol


Clopidol is a chemical compound used primarily as a coccidiostat, a type of medicinal drug that is used to prevent and treat coccidiosis, a parasitic disease in animals. It is a white, crystalline substance that is soluble in organic solvents but not in water.

History[edit | edit source]

Clopidol was first synthesized in the 1950s and has been used in veterinary medicine since the 1960s. It was initially used in the poultry industry to control coccidiosis in chickens, but its use has since expanded to other animals, including turkeys and rabbits.

Mechanism of Action[edit | edit source]

Clopidol works by inhibiting the enzyme dihydrofolate reductase, which is necessary for the synthesis of DNA and RNA. By blocking this enzyme, clopidol prevents the parasite from reproducing and spreading in the host animal.

Usage[edit | edit source]

Clopidol is typically administered orally, either in the form of a feed additive or a water-soluble powder. The dosage varies depending on the species and size of the animal, as well as the severity of the infection.

Side Effects[edit | edit source]

While clopidol is generally considered safe, it can cause side effects in some animals. These can include loss of appetite, weight loss, and in rare cases, neurological symptoms such as tremors and seizures.

Regulatory Status[edit | edit source]

In many countries, including the United States and the European Union, clopidol is approved for use in food-producing animals. However, there are strict regulations regarding its use, including withdrawal periods to ensure that residues of the drug do not remain in the meat or eggs of treated animals.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD