Codeine/aspirin
Codeine/Aspirin is a combination drug that contains both codeine and aspirin. It is used primarily for the relief of moderate to severe pain.
Composition[edit | edit source]
The drug is composed of two active ingredients: codeine, an opioid analgesic, and aspirin, a nonsteroidal anti-inflammatory drug (NSAID). The combination of these two drugs allows for effective pain management, as they work in different ways to alleviate pain.
Mechanism of Action[edit | edit source]
Codeine works by binding to opioid receptors in the brain, which reduces the perception of pain. Aspirin, on the other hand, works by inhibiting the production of prostaglandins, chemicals in the body that cause inflammation and increase the sensitivity of pain receptors.
Uses[edit | edit source]
Codeine/Aspirin is used to treat moderate to severe pain. It may also be used to reduce fever and relieve inflammatory conditions such as rheumatoid arthritis.
Side Effects[edit | edit source]
Common side effects of Codeine/Aspirin include nausea, vomiting, constipation, lightheadedness, and dizziness. Serious side effects may include breathing difficulties, severe drowsiness, and allergic reactions.
Precautions[edit | edit source]
Patients with a history of allergy to aspirin or codeine, asthma, bleeding or clotting disorders, stomach ulcers, or kidney or liver disease should use this medication with caution. It is also not recommended for use during pregnancy or breastfeeding.
Interactions[edit | edit source]
Codeine/Aspirin may interact with other medications, including other pain relievers, blood thinners, and certain antidepressants. It is important to inform healthcare providers of all medications being taken to avoid potential interactions.
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Contributors: Prab R. Tumpati, MD