Colchicum
Information about the plant genus Colchicum and its medical uses
Colchicum is a genus of flowering plants in the family Colchicaceae, commonly known as autumn crocus, meadow saffron, or naked ladies. The genus is native to Europe, North Africa, and parts of Asia.
Description[edit | edit source]
Colchicum species are perennial herbaceous plants that grow from corms. They are known for their large, showy flowers that resemble those of the true crocus, although they are not closely related. The flowers typically bloom in autumn, hence the name "autumn crocus."
Toxicity[edit | edit source]
All parts of the plant are toxic if ingested, containing alkaloids such as colchicine. Colchicine is a potent mitotic inhibitor and is used in medicine to treat gout and familial Mediterranean fever. However, due to its toxicity, it must be used with caution.
Medical Uses[edit | edit source]
Colchicine, derived from Colchicum species, is primarily used in the treatment of acute gout attacks. It works by reducing inflammation and decreasing the build-up of uric acid crystals in the joints. It is also used in the management of familial Mediterranean fever, a genetic disorder that causes recurrent fevers and inflammation.
Cultivation[edit | edit source]
Colchicum species are cultivated for their attractive flowers. They prefer well-drained soil and a sunny position. The corms are typically planted in late summer or early autumn.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD