Commensal bacteria
Commensal bacteria are a type of microorganism that live in various parts of the human body, including the skin, mouth, gastrointestinal tract, and vagina. They are part of the human microbiota, which consists of all the microorganisms that reside on and within human beings.
Overview[edit | edit source]
Commensal bacteria are typically non-pathogenic, meaning they do not cause disease under normal circumstances. Instead, they live in a symbiotic relationship with their host, in which both the bacteria and the host benefit. The host provides a habitat and nutrients for the bacteria, while the bacteria help to protect the host from harmful pathogens, aid in digestion, and contribute to the host's immune system.
Role in the Immune System[edit | edit source]
Commensal bacteria play a crucial role in the development and function of the immune system. They help to train the immune system to recognize and respond to harmful pathogens, while also helping to prevent overactive immune responses that can lead to autoimmune diseases.
Role in Digestion[edit | edit source]
In the gastrointestinal tract, commensal bacteria aid in the digestion of food. They help to break down complex carbohydrates and proteins that the human body cannot digest on its own. They also produce certain vitamins, such as vitamin K and some B vitamins, that are essential for human health.
Role in Disease[edit | edit source]
While commensal bacteria are typically beneficial, they can sometimes contribute to disease. For example, if the balance of commensal bacteria in the gut is disrupted, it can lead to conditions such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Some commensal bacteria can also become pathogenic under certain conditions, such as when the immune system is weakened or when they are able to enter parts of the body where they do not normally reside.
See Also[edit | edit source]
- Human microbiota
- Symbiosis
- Pathogen
- Autoimmune disease
- Irritable bowel syndrome
- Inflammatory bowel disease
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Contributors: Prab R. Tumpati, MD