Complex partial status epilepticus

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Complex partial status epilepticus
Synonyms Focal impaired awareness status epilepticus
Pronounce N/A
Specialty N/A
Symptoms Prolonged seizures with impaired awareness
Complications Brain damage, cognitive impairment
Onset Any age
Duration More than 30 minutes
Types Temporal lobe epilepsy, frontal lobe epilepsy
Causes Brain injury, stroke, infection, tumor
Risks Epilepsy, anticonvulsant withdrawal
Diagnosis EEG, neuroimaging
Differential diagnosis Absence status epilepticus, non-convulsive status epilepticus
Prevention Anticonvulsant medication adherence
Treatment Benzodiazepines, antiepileptic drugs
Medication N/A
Prognosis Variable, depends on underlying cause and treatment
Frequency Rare
Deaths N/A


Complex partial status epilepticus (CPSE) is a type of status epilepticus that is characterized by recurrent or ongoing seizures that affect a part of the brain. Unlike generalized status epilepticus, which affects the entire brain, CPSE is localized to a specific region. This condition is a serious medical emergency that requires immediate treatment to prevent long-term neurological damage or death.

Symptoms[edit | edit source]

The symptoms of complex partial status epilepticus can vary depending on the part of the brain that is affected. Common symptoms include:

Causes[edit | edit source]

Complex partial status epilepticus can be caused by a variety of factors, including:

Diagnosis[edit | edit source]

Diagnosis of complex partial status epilepticus is typically made based on the patient's symptoms and medical history, as well as neurological examination and electroencephalogram (EEG) testing. An EEG can detect abnormal electrical activity in the brain that is characteristic of seizures.

Treatment[edit | edit source]

Treatment for complex partial status epilepticus typically involves the use of antiepileptic drugs to stop the seizures. In some cases, surgery may be necessary to remove a brain tumor or other underlying cause of the seizures.

Prognosis[edit | edit source]

The prognosis for complex partial status epilepticus can vary widely depending on the underlying cause of the seizures and the patient's overall health. With prompt and appropriate treatment, many patients can achieve good seizure control and quality of life.

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Contributors: Prab R. Tumpati, MD