Copine 3

1. Copine 3

Copine 3 is a member of the copine family of proteins, which are calcium-dependent phospholipid-binding proteins. These proteins are thought to be involved in various cellular processes, including membrane trafficking, signal transduction, and cell-cell communication.

Structure

Copine 3, like other members of the copine family, contains two C2 domains at the N-terminus and an A domain at the C-terminus. The C2 domains are responsible for binding to phospholipids in a calcium-dependent manner, while the A domain is thought to mediate interactions with other proteins.

Function

The exact function of Copine 3 is not fully understood, but it is believed to play a role in intracellular signaling pathways. It may be involved in the regulation of protein kinase C and other signaling molecules. Copine 3 has also been implicated in the regulation of cell adhesion and migration, processes that are critical for tissue development and wound healing.

Clinical Significance

Alterations in the expression of Copine 3 have been observed in certain cancers, suggesting that it may play a role in tumor progression. Further research is needed to elucidate its potential as a biomarker or therapeutic target in cancer treatment.

Research

Studies on Copine 3 are ongoing to better understand its role in cellular processes and its potential implications in disease. Researchers are particularly interested in its interactions with other proteins and its involvement in calcium signaling pathways.

See Also

• Copine family
• Calcium signaling
• Phospholipid-binding proteins

External Links

• [Copine 3 at Wikidata](https://www.wikidata.org/wiki/Q123456)

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