Cords of Billroth

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Cords of Billroth are anatomical structures found in the spleen. They are named after the Austrian physician Theodor Billroth, who first described them in the 19th century.

Etymology[edit | edit source]

The Cords of Billroth are named after Theodor Billroth, an Austrian physician and surgeon who is generally regarded as the founder of modern abdominal surgery. His contributions to the field of medicine also include the first successful gastrectomy for gastric cancer.

Anatomy[edit | edit source]

The Cords of Billroth, also known as red pulp cords, are located in the red pulp of the spleen. They consist of loose connective tissue filled with blood cells, including erythrocytes, platelets, and different types of leukocytes. The cords are separated by the sinusoids of the spleen, which are lined by endothelial cells and allow for the passage of blood cells and plasma.

Function[edit | edit source]

The primary function of the Cords of Billroth is to filter the blood of antigens, microorganisms, and damaged or old blood cells. This is facilitated by the macrophages present in the cords, which phagocytose and destroy these unwanted elements. The cords also serve as a reservoir for blood cells and platelets, which can be released into the circulation when needed.

Clinical significance[edit | edit source]

Abnormalities in the structure or function of the Cords of Billroth can lead to various medical conditions. For example, splenomegaly (enlargement of the spleen) can occur if the cords become congested with blood cells. In contrast, hyposplenism (reduced spleen function) can result if the cords are damaged or destroyed, for instance in sickle cell disease or following splenectomy (surgical removal of the spleen).

See also[edit | edit source]

Cords of Billroth Resources
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Contributors: Prab R. Tumpati, MD