Polyvinylpolypyrrolidone

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(Redirected from Crospovidone)

Polyvinylpolypyrrolidone (also known as PVPP or Crospovidone) is a highly cross-linked modification of polyvinylpyrrolidone (PVP). It is used as a disintegrant in pharmaceutical tablets and is also used in the wine industry as a fining agent for white wines or some beers.

Chemical Structure[edit]

Polyvinylpolypyrrolidone is a water-insoluble polymer prepared from the monomer N-vinylpyrrolidone. It is a highly cross-linked version of polyvinylpyrrolidone, with the degree of cross-linking sufficient to render the polymer water-insoluble.

Uses[edit]

Pharmaceutical Industry[edit]

In the pharmaceutical industry, PVPP is used as a disintegrant, a substance that promotes the breakup of a tablet in the digestive tract after ingestion. It is included in the formulation of tablets for this purpose.

Wine Industry[edit]

In the wine industry, PVPP is used as a fining agent for white wines or some beers. It removes polyphenols, compounds that can cause astringency and some types of hazing in wines.

Safety[edit]

PVPP is generally considered safe for use in the pharmaceutical and food industries. It is not absorbed by the body and is therefore considered non-toxic and non-allergenic.

See Also[edit]

References[edit]



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