D1-like

D1-like receptor is a type of dopamine receptor that is a protein found in the brain. It is one of five subtypes of dopamine receptors, and is grouped into the D1-like class along with the D5 receptor. D1-like receptors are linked to the intracellular adenylyl cyclase-cAMP signal transduction pathway.

Function

D1-like receptors are involved in a variety of neurological processes, including locomotion, reward, learning, and memory. They are also implicated in several disorders, such as schizophrenia, drug addiction, and Parkinson's disease.

Structure

The D1-like receptor is a G protein-coupled receptor that is located on the cell membrane. It is composed of seven transmembrane domains, an extracellular N-terminus, and an intracellular C-terminus.

Pharmacology

D1-like receptors can be targeted by a variety of drugs, including antipsychotics, antidepressants, and stimulants. These drugs can either increase or decrease the activity of the D1-like receptor, depending on their mechanism of action.

See also

• D2-like receptor
• Dopamine receptor D1
• Dopamine receptor D5

References

D1-like Resources
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