DCMU

From WikiMD's Wellness Encyclopedia

DCMU (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is a compound used in scientific research to inhibit photosynthesis. It was introduced in 1954 as a herbicide. DCMU is a highly specific inhibitor of plastoquinone, which is involved in the photosynthetic electron transport chain within the chloroplast thylakoid membrane.

Mechanism of action[edit | edit source]

DCMU inhibits photosynthesis by blocking electron transport at the plastoquinone-quinone (PQ) binding site within Photosystem II (PS II). This prevents the reduction of PQ by the PS II reaction center, thereby halting the photosynthetic electron transport chain. As a result, the energy from absorbed light cannot be converted into chemical energy, and photosynthesis is inhibited.

Uses[edit | edit source]

DCMU is primarily used in scientific research as a specific inhibitor of photosynthesis. It is also used as a herbicide, as it can kill plants by inhibiting their ability to photosynthesize.

Safety[edit | edit source]

DCMU is moderately toxic to humans and animals. It can cause skin and eye irritation, and ingestion or inhalation can lead to symptoms such as nausea, vomiting, and difficulty breathing. It is also toxic to aquatic organisms and can cause long-term adverse effects in the environment.

See also[edit | edit source]

DCMU Resources
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Contributors: Prab R. Tumpati, MD