DR2
DR2 or HLA-DR2 is a human leukocyte antigen serotype within HLA-DR serogroup. The serotype is determined by the antibody recognition of β2 subset of HLA-DR. It is a cell surface receptor involved in immune system regulation.
Function[edit | edit source]
DR2 is a part of the HLA class II molecule group, which are involved in the immune system's ability to distinguish self from non-self. These molecules are integral to the immune response, including antigen presentation, T cell activation, and cytokine production.
Associations with diseases[edit | edit source]
HLA-DR2 serotype has been associated with several autoimmune and infectious diseases, including multiple sclerosis, narcolepsy, and Lyme disease. However, the exact role of HLA-DR2 in these diseases is not fully understood and is the subject of ongoing research.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
