DZIP1

Ideogram_human_chromosome_13

DZIP1

DZIP1 is a gene that encodes a protein involved in cellular processes. It plays a role in regulating gene expression and protein degradation pathways. DZIP1 is known to interact with various other proteins and is implicated in several biological functions.

Function

DZIP1 functions as a regulator of protein degradation through the ubiquitin-proteasome system. It interacts with specific target proteins and facilitates their ubiquitination, marking them for degradation. Additionally, DZIP1 is involved in the regulation of gene expression by modulating the activity of transcription factors.

Structure

The DZIP1 gene encodes a protein that consists of several domains, including a RING finger domain and a coiled-coil domain. These domains are essential for its interactions with other proteins and its role in protein degradation pathways.

Interactions

DZIP1 interacts with various proteins involved in different cellular processes. It has been shown to interact with components of the ubiquitin-proteasome system, as well as transcription factors and signaling molecules. These interactions are crucial for the proper functioning of DZIP1 in regulating protein degradation and gene expression.

Clinical Significance

Mutations in the DZIP1 gene have been associated with certain diseases and disorders. Dysregulation of DZIP1 expression or function can lead to abnormal protein turnover and gene expression, which may contribute to the development of certain conditions.