D amphetamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

D-Amphetamine is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.

Pharmacology[edit | edit source]

D-Amphetamine is a sympathomimetic amine that promotes release of the neurotransmitters dopamine and norepinephrine in the brain. It also inhibits monoamine oxidase, an enzyme that breaks down dopamine and norepinephrine.

Medical uses[edit | edit source]

D-Amphetamine is used in the treatment of ADHD, where it is believed to improve focus and impulse control. It is also used in the treatment of narcolepsy to help patients stay awake during the day.

Side effects[edit | edit source]

Common side effects of D-Amphetamine include restlessness, insomnia, and loss of appetite. More serious side effects can include heart problems, psychosis, and addiction.

History[edit | edit source]

D-Amphetamine was first synthesized in the late 19th century and was used in nasal decongestants and bronchial inhalers. In the 1930s, it was approved by the Food and Drug Administration (FDA) for the treatment of ADHD and narcolepsy.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD