Dan M. Granoff

American physician and researcher

Dan M. Granoff in 2017

Dan M. Granoff is an American physician and researcher renowned for his contributions to the field of immunology and infectious diseases. His work has significantly advanced the understanding and prevention of bacterial meningitis, particularly through the development of vaccines.

Early Life and Education

Dan M. Granoff was born in the United States. He pursued his undergraduate studies in biology, which laid the foundation for his interest in medical research. Granoff earned his medical degree from a prestigious medical school, where he developed a keen interest in infectious diseases and immunology.

Career

Granoff began his career as a researcher focusing on bacterial pathogens. He joined the Children's Hospital Oakland Research Institute (CHORI), where he became a leading figure in the study of Neisseria meningitidis, the bacterium responsible for meningococcal disease. His research has been pivotal in understanding the pathogenesis of this bacterium and in developing effective vaccines.

Research Contributions

Granoff's research has primarily focused on the development of vaccines against meningococcal disease. He has been instrumental in the development of the MenB vaccine, which targets serogroup B of Neisseria meningitidis. His work has also explored the immunogenicity and safety of various vaccine formulations, contributing to the broader field of vaccine development.

Vaccine Development

One of Granoff's significant achievements is his contribution to the development of the MenB vaccine. This vaccine has been crucial in reducing the incidence of meningococcal disease caused by serogroup B, which was previously difficult to target due to the bacterium's complex polysaccharide capsule.

Awards and Honors

Throughout his career, Granoff has received numerous awards and honors for his contributions to medical research and public health. His work has been recognized by various professional organizations, and he has been invited to speak at numerous international conferences on infectious diseases and vaccines.

Legacy

Dan M. Granoff's work has had a lasting impact on public health, particularly in the prevention of bacterial meningitis. His research has not only contributed to the development of life-saving vaccines but has also advanced the scientific understanding of bacterial pathogenesis and immune responses.

Related Pages

• Neisseria meningitidis
• Meningococcal vaccine
• Immunology
• Infectious diseases