Danio rerio

From WikiMD's Food, Medicine & Wellness Encyclopedia

Danio rerio, commonly known as the zebrafish, is a tropical freshwater fish belonging to the minnow family Cyprinidae. It is a popular model organism in scientific research due to its genetic similarity to humans and its transparent embryos, which allow direct observation of developmental processes. This article provides an overview of Danio rerio, including its taxonomy, habitat, physical characteristics, and significance in research.

Taxonomy[edit | edit source]

Danio rerio was first described in 1822 by Francis Hamilton, a Scottish physician and zoologist. It is classified within the genus Danio, part of the larger family Cyprinidae, which includes other small fish species commonly found in freshwater habitats.

Habitat and Distribution[edit | edit source]

Danio rerio is native to the southeastern Himalayan region, including India, Nepal, Bangladesh, and Myanmar. It inhabits a variety of freshwater environments such as streams, rice paddies, and ponds. The species prefers shallow, slow-moving waters with abundant vegetation.

Physical Characteristics[edit | edit source]

The zebrafish is a small fish, typically reaching up to 5 centimeters (2 inches) in length. It is named for its distinctive horizontal stripes, reminiscent of a zebra's pattern, which run along the length of its body. The stripes are thought to serve as camouflage against predators. Zebrafish have a fusiform body shape, which is streamlined and allows for rapid swimming.

Reproduction and Development[edit | edit source]

Zebrafish are oviparous, with females laying hundreds of eggs at a time. Fertilization occurs externally, and the development of embryos is rapid. One of the most remarkable aspects of zebrafish development is the transparency of the embryos, which enables researchers to observe the process of organ formation and early development without invasive techniques.

Use in Research[edit | edit source]

Danio rerio has become a vital model organism in various fields of biological research, including genetics, developmental biology, toxicology, and neuroscience. Its genetic makeup is well understood, with a fully sequenced genome that shares many similarities with the human genome. This, along with the species' rapid reproductive cycle and the transparency of its embryos, makes it an invaluable tool for studying gene function, embryonic development, and the effects of genetic mutations.

Researchers also use zebrafish to study the impact of environmental toxins on development and health, as well as to investigate the genetic basis of diseases. The ease of genetic manipulation in zebrafish has led to the creation of numerous mutant and transgenic lines, further expanding its utility as a model organism.

Conservation Status[edit | edit source]

Currently, Danio rerio is not considered to be at risk of extinction and is classified as Least Concern by the International Union for Conservation of Nature (IUCN). However, habitat destruction and pollution in its native range pose potential threats to wild populations.

Conclusion[edit | edit source]

Danio rerio plays a crucial role in advancing our understanding of biological processes and disease mechanisms. Its ease of care, rapid life cycle, and genetic tractability make it an ideal model organism for scientific research. As studies on zebrafish continue, this small fish is likely to contribute significantly to our knowledge of genetics, development, and environmental science.


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Contributors: Prab R. Tumpati, MD