Darodipine
Darodipine (also known as PY 108-068) is a calcium channel blocker that is used in the treatment of hypertension. It is a dihydropyridine derivative and is similar to other calcium channel blockers such as amlodipine, felodipine, and isradipine.
Pharmacology[edit | edit source]
Darodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. It binds to dihydropyridine and phenylalkylamine binding sites. The binding is voltage-dependent and is enhanced at depolarized membrane potentials.
Clinical Use[edit | edit source]
Darodipine is used in the treatment of hypertension. It lowers blood pressure by relaxing the smooth muscle in the walls of the arteries, causing them to open wider. This reduces the pressure in the arteries, making it easier for the heart to pump blood.
Side Effects[edit | edit source]
Like other calcium channel blockers, darodipine can cause a number of side effects. These can include dizziness, flushing, headache, nausea, palpitations, and edema. In rare cases, it can cause serious side effects such as arrhythmia and hypotension.
See Also[edit | edit source]
Darodipine Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
References[edit | edit source]
External Links[edit | edit source]
- Darodipine on Drugs.com
- Darodipine on PubChem
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD