Dehydroandrosterone
Dehydroandrosterone[edit | edit source]
Chemical structure of Dehydroandrosterone
Dehydroandrosterone (DHA) is a naturally occurring steroid hormone that is produced in the adrenal glands and gonads. It is a derivative of androsterone and is closely related to dehydroepiandrosterone (DHEA). DHA plays a crucial role in various physiological processes in the human body.
Chemical Properties[edit | edit source]
DHA, also known as 5α-androst-16-en-3β-ol, has a molecular formula of C19H28O2 and a molecular weight of 288.42 g/mol. It is a white crystalline powder that is insoluble in water but soluble in organic solvents such as ethanol and chloroform. The chemical structure of DHA consists of a steroid backbone with a double bond at the 5α position and a hydroxyl group at the 3β position.
Biological Functions[edit | edit source]
DHA is involved in several important biological functions in the body. It serves as a precursor for the synthesis of other steroid hormones, including testosterone and estrogen. DHA is also known to have anti-inflammatory and immunomodulatory effects, which contribute to its role in maintaining immune system homeostasis.
Health Benefits[edit | edit source]
Research suggests that DHA may have various health benefits. It has been studied for its potential anti-aging properties, as it is believed to support the production of collagen and elastin, which are essential for maintaining youthful skin. DHA has also been investigated for its potential role in improving cognitive function and reducing the risk of neurodegenerative diseases such as Alzheimer's.
Clinical Applications[edit | edit source]
Due to its potential health benefits, DHA has been explored for various clinical applications. It has been used as a supplement in the treatment of adrenal insufficiency, a condition characterized by inadequate production of adrenal hormones. DHA has also been studied for its potential use in hormone replacement therapy and as an adjunct treatment for certain autoimmune disorders.
References[edit | edit source]
See Also[edit | edit source]
External Links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
