Deoxymiroestrol

From WikiMD's Wellness Encyclopedia

Deoxymiroestrol is a phytoestrogen that is found in the plant Pueraria mirifica. It is structurally similar to miroestrol, another phytoestrogen found in the same plant. Deoxymiroestrol is believed to be the precursor to miroestrol.

Chemical Structure[edit | edit source]

Deoxymiroestrol has a similar chemical structure to miroestrol, but it lacks a hydroxyl group at the 3' position. This difference in structure is believed to be the reason why deoxymiroestrol is less potent than miroestrol as an estrogen.

Biological Activity[edit | edit source]

Deoxymiroestrol has been found to have estrogenic activity, although it is less potent than miroestrol. It is believed to act as a selective estrogen receptor modulator (SERM), which means it can either activate or inhibit the estrogen receptor depending on the tissue.

Pharmacology[edit | edit source]

The pharmacology of deoxymiroestrol is not well understood. It is believed to be metabolized in the body to miroestrol, which is more potent as an estrogen. However, more research is needed to confirm this.

Uses[edit | edit source]

Deoxymiroestrol is used in traditional medicine in Thailand for its supposed rejuvenating properties. It is also used in some dietary supplements and cosmetics.

Safety[edit | edit source]

The safety of deoxymiroestrol is not well established. Some studies have suggested that it may have potential health risks, including the possibility of promoting the growth of certain types of cancer cells. However, more research is needed to confirm these findings.

See Also[edit | edit source]

Deoxymiroestrol Resources
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Contributors: Prab R. Tumpati, MD