Dermatomal mesenchyme

Dermatomal mesenchyme
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Dermatomal mesenchyme refers to the mesenchyme that is associated with a specific dermatome. A dermatome is an area of skin that is mainly supplied by a single spinal nerve.

Development

During embryonic development, the mesoderm differentiates into several types of tissue, including the paraxial mesoderm, which further segments into somites. Each somite differentiates into three parts: the sclerotome, the myotome, and the dermatome. The dermatome gives rise to the dermis of the skin, and the associated mesenchyme is known as dermatomal mesenchyme.

Function

The dermatomal mesenchyme plays a crucial role in the development of the integumentary system, particularly in the formation of the dermis. It provides the necessary connective tissue framework and supports the epidermis.

Clinical significance

Abnormal development of dermatomal mesenchyme can lead to various congenital disorders affecting the skin and connective tissues. Understanding the development and function of dermatomal mesenchyme is important in the field of regenerative medicine and tissue engineering.

See also

• Dermatome (anatomy)
• Mesenchyme
• Embryonic development
• Integumentary system

External links

• Dermatomal mesenchyme on WikiMD