Dibenzoylmorphine

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Dibenzoylmorphine


Dibenzoylmorphine is a semi-synthetic morphine derivative in which two acetyl groups are replaced by benzoyl groups. It is often used in scientific research and has a similar effect to morphine in terms of pain relief and sedation.

Chemistry[edit | edit source]

Dibenzoylmorphine is a benzoyl ester of morphine, meaning it is morphine with two benzoyl groups attached. The chemical formula for dibenzoylmorphine is C29H23NO5. It is a white, crystalline substance that is soluble in water and alcohol.

Pharmacology[edit | edit source]

Like morphine, dibenzoylmorphine acts on the mu-opioid receptor in the brain to produce its effects. It is a potent analgesic, providing pain relief, and also has sedative properties. However, it is less potent than morphine and has a slower onset of action.

Medical Use[edit | edit source]

Dibenzoylmorphine is not commonly used in clinical practice due to its lower potency and slower onset of action compared to morphine. However, it is often used in scientific research to study the effects of opioids on the brain and body.

Legal Status[edit | edit source]

In many countries, including the United States, dibenzoylmorphine is a Schedule I drug under the Controlled Substances Act, meaning it has a high potential for abuse and no accepted medical use.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD