Dibutepinephrine

From WikiMD.com Medical Encyclopedia

Overview of the chemical compound Dibutepinephrine


Dibutepinephrine is a synthetic sympathomimetic amine that acts as a vasoconstrictor and bronchodilator. It is primarily used in medical settings to manage conditions such as hypotension and bronchospasm.

Chemical Structure[edit | edit source]

Error creating thumbnail:
Chemical structure of Dibutepinephrine

Dibutepinephrine is a derivative of epinephrine, with modifications that enhance its stability and duration of action. The chemical structure of Dibutepinephrine includes a catecholamine backbone with additional alkyl groups that increase its lipophilicity.

Pharmacology[edit | edit source]

Dibutepinephrine functions by stimulating adrenergic receptors, specifically the alpha and beta receptors. This dual action results in increased vasoconstriction and bronchodilation, making it effective in treating conditions like anaphylaxis and asthma.

Mechanism of Action[edit | edit source]

The drug binds to adrenergic receptors on the surface of target cells, leading to the activation of adenylate cyclase and an increase in cyclic adenosine monophosphate (cAMP) levels. This cascade results in the relaxation of smooth muscle in the airways and constriction of blood vessels.

Clinical Uses[edit | edit source]

Dibutepinephrine is used in emergency medicine for its rapid onset of action in reversing severe allergic reactions and managing acute asthma attacks. It is also employed in surgical settings to maintain blood pressure during anesthesia.

Side Effects[edit | edit source]

Common side effects of Dibutepinephrine include tachycardia, hypertension, and anxiety. Due to its potent effects, careful monitoring is required to avoid complications such as arrhythmias and myocardial infarction.

Administration[edit | edit source]

Dibutepinephrine is typically administered via intravenous or intramuscular injection. The route of administration depends on the urgency of the clinical situation and the desired speed of onset.

Related Pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD