Dichloroisoprenaline

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Dichloroisoprenaline (also known as DCI) is a synthetic compound that belongs to the chemical class of halogenated hydrocarbons. It is a non-selective beta blocker and vasodilator that has been used in the treatment of hypertension and glaucoma. However, its use has been largely discontinued due to the availability of safer and more effective alternatives.

History[edit | edit source]

Dichloroisoprenaline was first synthesized in the 1950s and was one of the first beta blockers to be developed. It was initially used in the treatment of hypertension and glaucoma, but its use has since been largely discontinued due to the availability of safer and more effective alternatives.

Pharmacology[edit | edit source]

As a non-selective beta blocker, dichloroisoprenaline works by blocking the action of epinephrine (adrenaline) and norepinephrine (noradrenaline) on beta receptors, which are found in the heart and blood vessels. This reduces heart rate, blood pressure, and strain on the heart.

As a vasodilator, dichloroisoprenaline works by relaxing and widening the blood vessels, which allows blood to flow more easily and reduces blood pressure.

Side Effects[edit | edit source]

Like all medications, dichloroisoprenaline can cause side effects. These may include dizziness, fatigue, nausea, and shortness of breath. In rare cases, it can cause serious side effects such as heart failure, stroke, and death.

See Also[edit | edit source]

References[edit | edit source]

Dichloroisoprenaline Resources
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Contributors: Prab R. Tumpati, MD