Digoxin immune fab
Digoxin Immune Fab[edit | edit source]
Digoxin Immune Fab is a type of antibody that is used as an antidote in the treatment of life-threatening digoxin toxicity or overdose. It is also known as Digibind, and is a product of GlaxoSmithKline.
Mechanism of Action[edit | edit source]
Digoxin Immune Fab works by binding to the digoxin, making it unable to exert its effects on the body. This binding forms a complex that is then excreted by the kidneys.
Indications[edit | edit source]
Digoxin Immune Fab is indicated for use in patients with life-threatening digoxin toxicity or overdose. This can occur as a result of chronic ingestion of excessive amounts of digoxin, or from an acute overdose.
Side Effects[edit | edit source]
The most common side effects of Digoxin Immune Fab include hypokalemia, hypomagnesemia, and worsening of congestive heart failure.
Contraindications[edit | edit source]
Digoxin Immune Fab is contraindicated in patients with known hypersensitivity to ovine (sheep) proteins or to the product itself.
Dosage and Administration[edit | edit source]
The dosage of Digoxin Immune Fab is based on the amount of digoxin to be neutralized. The product is administered intravenously.
References[edit | edit source]
See Also[edit | edit source]
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