Dihydrexidine

Dihydrexidine is a dopamine receptor agonist. It is most selective for the D1 and D5 receptors, but also has affinity for the D2 and D3 receptors. Dihydrexidine has been investigated for its potential use in the treatment of Parkinson's disease and schizophrenia.

Pharmacology

Dihydrexidine is a full agonist at the D1 and D5 dopamine receptors, and is the first drug of this kind to be discovered. It also has affinity for the D2 and D3 receptors, but is less selective for these. Dihydrexidine has been shown to possess potent antiparkinsonian effects, and has been investigated for potential use in the treatment of Parkinson's disease.

Clinical uses

Dihydrexidine has been investigated for its potential use in the treatment of Parkinson's disease. It has been shown to improve motor function in animal models of the disease, and has been investigated in clinical trials in humans. Dihydrexidine has also been investigated for its potential use in the treatment of schizophrenia. It has been suggested that the drug may have antipsychotic effects, due to its action at the D1 and D5 receptors.

Side effects

The side effects of dihydrexidine are not well known, as the drug is still under investigation. However, it has been suggested that the drug may cause hypotension (low blood pressure), due to its action at the D2 and D3 receptors.

See also

• Dopamine receptor
• Dopamine agonist
• Parkinson's disease
• Schizophrenia

Dihydrexidine Resources
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