Disalcid
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Disalcid is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to treat pain and inflammation associated with various conditions such as arthritis, muscle pain, and fever. It is known chemically as sodium 2-(2-hydroxybenzoyl)oxybenzoate. Disalcid is marketed under various brand names including Salsitab among others.
Medical uses[edit | edit source]
Disalcid is used to relieve pain, reduce inflammation, and lower fever. It is particularly effective in treating symptoms of arthritis, including osteoarthritis and rheumatoid arthritis. The medication works by inhibiting the production of substances in the body that cause inflammation and pain.
Mechanism of action[edit | edit source]
As an NSAID, Disalcid works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are chemicals in the body that promote inflammation, pain, and fever. By blocking COX enzymes, Disalcid reduces the levels of prostaglandins, thus alleviating pain and inflammation.
Side effects[edit | edit source]
Common side effects of Disalcid include gastrointestinal issues such as nausea, vomiting, diarrhea, and stomach ulcers. It can also cause dizziness, headache, and rash. Long-term use of NSAIDs like Disalcid can increase the risk of cardiovascular events such as heart attack and stroke, as well as serious gastrointestinal damage.
Contraindications[edit | edit source]
Disalcid should not be used by individuals who have had allergic reactions to aspirin or other NSAIDs. It is also contraindicated in patients with severe kidney or liver disease, gastrointestinal bleeding, or those who are pregnant or breastfeeding without consultation with a healthcare provider.
Pharmacokinetics[edit | edit source]
The details on the absorption, metabolism, and excretion of Disalcid are not extensively documented. However, like other NSAIDs, it is likely absorbed in the gastrointestinal tract and metabolized in the liver.
See also[edit | edit source]
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