Dolutegravir/lamivudine/tenofovir disoproxil
Dolutegravir/lamivudine/tenofovir disoproxil is a fixed-dose combination antiretroviral medication used in the treatment of HIV/AIDS. It combines three active ingredients: dolutegravir, lamivudine, and tenofovir disoproxil.
Composition[edit | edit source]
The medication is composed of three active ingredients. Dolutegravir is an integrase inhibitor, which prevents the virus from integrating its genetic material into the host cell. Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI), which blocks a critical step in the virus's replication process. Tenofovir disoproxil is a prodrug of tenofovir, an antiretroviral of the nucleotide analogue reverse transcriptase inhibitor (NtRTI) class.
Usage[edit | edit source]
Dolutegravir/lamivudine/tenofovir disoproxil is used in the treatment of HIV/AIDS. It is taken orally, usually once a day. The medication is used in combination with other antiretroviral drugs as part of an antiretroviral therapy (ART) regimen.
Side Effects[edit | edit source]
Common side effects include nausea, diarrhea, and headache. Serious side effects may include liver problems, lactic acidosis, and reactivation of hepatitis B in those previously infected.
Interactions[edit | edit source]
Dolutegravir/lamivudine/tenofovir disoproxil can interact with other medications, including other antiretrovirals, antacids, and certain anti-seizure medications. It is important to discuss all medications and supplements with a healthcare provider before starting treatment.
See Also[edit | edit source]
- Antiretroviral therapy
- HIV/AIDS
- Integrase inhibitor
- Nucleoside reverse transcriptase inhibitor
- Prodrug
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