Dorea

Dorea

Dorea is a genus of bacteria within the family Lachnospiraceae. These bacteria are part of the human gut microbiota and play a role in the digestion of complex carbohydrates. The genus was named after the British microbiologist Dorothy M. Jones, who made significant contributions to the study of gut microbiota.

Characteristics

Dorea species are Gram-positive, non-spore-forming, and obligately anaerobic. They are rod-shaped and typically found in the gastrointestinal tract of humans and other animals. These bacteria are known for their ability to ferment a variety of carbohydrates, producing short-chain fatty acids such as butyrate, which are beneficial for gut health.

Species

The genus Dorea includes several species, some of which are:

• Dorea formicigenerans
• Dorea longicatena
• Dorea massiliensis

Role in Human Health

Dorea species are considered to be part of the commensal microbiota of the human gut. They contribute to the maintenance of gut health by participating in the fermentation of dietary fibers and the production of short-chain fatty acids. These metabolic activities help in maintaining the integrity of the gut lining and modulating the immune system.

Research and Applications

Research on Dorea and other gut microbiota is ongoing, with studies focusing on their role in digestive health, immune function, and potential implications in various diseases such as inflammatory bowel disease and irritable bowel syndrome. Understanding the functions and interactions of these bacteria could lead to new therapeutic approaches for managing gut-related disorders.

See Also

• Gut microbiota
• Lachnospiraceae
• Short-chain fatty acids
• Anaerobic bacteria
• Human gastrointestinal tract