Dorello's canal

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Dorello's canal, also known as the petroclival canal, is a crucial anatomical structure located at the base of the skull. It serves as a passageway for several important structures, including the abducens nerve (cranial nerve VI) as it travels from the brainstem to the orbit. This canal is named after the Italian anatomist Enrico Dorello, who first described it in the early 20th century.

Anatomy: Dorello's canal is a narrow bony canal located in the petroclival region of the skull base. It is formed by the petrous part of the temporal bone and the clivus of the occipital bone. The canal is situated posterior to the cavernous sinus and medial to the petrous apex. Within the canal, the abducens nerve travels from its origin in the pons to the orbit, where it innervates the lateral rectus muscle responsible for outward eye movement.

Clinical Significance: Damage or compression of the abducens nerve within Dorello's canal can result in a condition known as abducens nerve palsy. Patients with this condition may experience double vision (diplopia) and difficulty moving one or both eyes laterally. Common causes of abducens nerve palsy include trauma, tumors, infections, and vascular lesions affecting the canal.

Diagnosis and Treatment: Diagnosis of abducens nerve palsy associated with Dorello's canal involvement typically involves a thorough neurological examination, imaging studies such as magnetic resonance imaging (MRI) or computed tomography (CT) scans, and possibly electrophysiological testing. Treatment options depend on the underlying cause and may include conservative management, surgical decompression, or targeted therapies to address specific etiologies.

Research and Future Directions: Ongoing research in the field of skull base anatomy and neurosurgery continues to shed light on the intricate structures within Dorello's canal. Advances in imaging technology and surgical techniques aim to improve outcomes for patients with conditions affecting this critical anatomical region.

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Contributors: Prab R. Tumpati, MD