Calcipotriene
(Redirected from Dovonex)
What is Calcipotriene?[edit | edit source]
- Calcipotriene (Sorilux, Dovonex) is a vitamin D analog used for the topical treatment of plaque psoriasis.
What are the uses of this medicine?[edit | edit source]
- Calcipotriene (Sorilux,Dovonex) is a prescription medicine used on the skin (topical) to treat plaque psoriasis of the scalp and body in people 4 years of age and older.
How does this medicine work?[edit | edit source]
- Calcipotriene is a synthetic vitamin D3 analog that has a similar receptor binding affinity as natural vitamin D3.
- However, the exact mechanism of action contributing to the clinical efficacy in the treatment of psoriasis is unknown.
Who Should Not Use this medicine ?[edit | edit source]
This medicine cannot be used in patients who:
- with known hypercalcemia
What drug interactions can this medicine cause?[edit | edit source]
- No formal drug interaction studies have been conducted with Calcipotriene.
Is this medicine FDA approved?[edit | edit source]
- It was patented in 1985 and approved for medical use in 1993.
How should this medicine be used?[edit | edit source]
Recommended dosage:
- Apply twice daily.
Administration:
- Apply a thin layer of calcipotriene foam twice daily to the affected areas and rub in gently and completely.
- Avoid contact with the face and eyes.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
- As 0.005%, foam
- Scalp Solution, 0.005%
- Calcipotriene Cream, 0.005%
- Calcipotriene ointment, 0.005%
This medicine is available in fallowing brand namesː
- SORILUX; DOVONEX
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
- application site erythema
- application site pain
Calcipotriene may cause serious side effects, including:
- Too much calcium in your blood
What special precautions should I follow?[edit | edit source]
- Contents are flammable. Instruct the patient the avoid fire, flame, and smoking during and immediately following application.
- Elevation of serum calcium has occurred with use of calcipotriene. If elevation in serum calcium outside the normal range should occur, discontinue treatment until normal calcium levels are restored.
- Avoid getting Calcipotriene on your face or in or near your eyes. If SORILUX Foam gets on your face or in your eyes, rinse well with water.
- Wash your hands after applying calcipotriene foam unless your hands are the affected site.
- Do not place calcipotriene foam in the refrigerator or freezer.
What to do in case of emergency/overdose?[edit | edit source]
Symptoms of overdosage may include:
- Elevated serum calcium
Can this medicine be used in pregnancy?[edit | edit source]
- Although there are no available data on the drug- associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes in pregnant women exposed to calcipotriene.
Can this medicine be used in children?[edit | edit source]
- The safety and effectiveness of calcipotriene have been established in pediatric patients age 4 years and older for topical treatment of plaque psoriasis of the scalp and body.
- The safety and effectiveness of calcipotriene in pediatric patients less than 4 years of age have not been established.
What are the active and inactive ingredients in this medicine?[edit | edit source]
- Active ingredient: calcipotriene
- Inactive ingredients: cetyl alcohol, dibasic sodium phosphate, dl-α-tocopherol, edetate disodium, isopropyl myristate, light mineral oil, polyoxyl 20 cetostearyl ether, propylene glycol, purified water, stearyl alcohol, and white petrolatum. The foam is dispensed from an aluminum can pressurized with a hydrocarbon (propane/n-butane/isobutane) propellant.
Who manufactures and distributes this medicine?[edit | edit source]
SORILUX:
- Distributed by:
Mayne Pharma Greenville, NC SORILUX is a registered trademark of Mayne Pharma LLC.
DOVONEX
- Distributed by:
Physicians Total Care, Inc.
What should I know about storage and disposal of this medication?[edit | edit source]
- Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C – 30°C (59°F – 86°F).
- Flammable. Contents under pressure. Do not puncture or incinerate. Do not expose to heat or store at temperatures above 120°F (49°C).
- Keep out of reach of children.
- Do not store Foam in the refrigerator or freezer.
Calcipotriene Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Deepika vegiraju, Prab R. Tumpati, MD, WikiMD