EHF (gene)

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EHF (gene)

The EHF gene, also known as ETS homologous factor, is a gene that is located on the 11th chromosome in humans. It is a member of the ETS family of transcription factors and is involved in a variety of functions including cellular development, cell proliferation, and apoptosis.[1]

Function[edit | edit source]

The EHF gene encodes a protein that functions as a transcriptional repressor and has been shown to downregulate the expression of genes involved in cell growth and proliferation. It is also involved in the regulation of epithelial cell differentiation and has been implicated in the development of prostate cancer and asthma.[2]

Clinical significance[edit | edit source]

Mutations in the EHF gene have been associated with a variety of diseases. For example, a mutation in this gene has been linked to an increased risk of prostate cancer. Additionally, variations in the EHF gene have been associated with susceptibility to asthma and other respiratory diseases.[3]

See also[edit | edit source]

References[edit | edit source]


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