EMB-FUBINACA

EMB-FUBINACA

EMB-FUBINACA is a synthetic cannabinoid that has been identified as a designer drug. It is a potent agonist of the cannabinoid receptors and is structurally related to other synthetic cannabinoids such as AB-FUBINACA and ADB-FUBINACA. These compounds are often found in products marketed as "herbal incense" or "spice," which are intended to mimic the effects of cannabis.

Chemical Structure and Properties

EMB-FUBINACA belongs to the indazole-3-carboxamide family of synthetic cannabinoids. Its chemical structure is characterized by the presence of a fluorobenzyl group and a methoxybenzyl group attached to the indazole core. The IUPAC name for EMB-FUBINACA is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide.

Molecular Formula

The molecular formula of EMB-FUBINACA is C21H23FN4O2.

Molecular Weight

The molecular weight of EMB-FUBINACA is 382.43 g/mol.

Pharmacology

EMB-FUBINACA acts as a potent agonist at the CB1 receptor and CB2 receptor, which are part of the endocannabinoid system. This system is involved in regulating various physiological processes, including mood, memory, and pain sensation. The activation of these receptors by synthetic cannabinoids like EMB-FUBINACA can lead to psychoactive effects similar to those of THC, the active component of cannabis.

Effects and Toxicity

The effects of EMB-FUBINACA can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause severe adverse effects such as anxiety, paranoia, hallucinations, and even acute toxicity leading to hospitalization. Cases of severe intoxication and fatalities have been reported in association with the use of synthetic cannabinoids like EMB-FUBINACA.

Legal Status

The legal status of EMB-FUBINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies continue to monitor and update the legal status of synthetic cannabinoids as new compounds are identified.

Detection and Analysis

EMB-FUBINACA can be detected in biological samples using advanced analytical techniques such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). These methods are essential for forensic investigations and toxicological analyses.

Also see

• Synthetic cannabinoids
• Cannabinoid receptor
• AB-FUBINACA
• ADB-FUBINACA
• Spice (drug)