ETS2

ETS2 (v-ets avian erythroblastosis virus E26 oncogene homolog 2) is a gene that encodes a protein which belongs to the ETS family of transcription factors. This protein plays a crucial role in various biological processes, including cell growth, differentiation, and apoptosis.

Function[edit | edit source]

The ETS2 gene is a member of the ETS family of transcription factors and is regulated by signaling pathways. These transcription factors are involved in a variety of biological processes, including cell growth, differentiation, apoptosis, and tissue remodeling. The ETS2 protein is a nuclear target for the ras-raf-MAPK signaling cascade.

Clinical significance[edit | edit source]

Alterations in the ETS2 gene are associated with several health conditions. For instance, an extra copy of the ETS2 gene is present in people with Down syndrome, which is thought to contribute to the characteristic features of this condition. Additionally, mutations in the ETS2 gene have been linked to various types of cancer, including leukemia and solid tumors.

Interactions[edit | edit source]

ETS2 has been shown to interact with:

References[edit | edit source]

External links[edit | edit source]

ETS2 at the US National Library of Medicine Medical Subject Headings (MeSH)

ETS2 Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.