Eicosanoyl-5-hydroxytryptamide

Eicosanoyl-5-hydroxytryptamide (EHT) is a bioactive compound found in coffee. It is a derivative of the neurotransmitter serotonin and the fatty acid eicosanoic acid. EHT has been studied for its potential neuroprotective effects and its role in promoting brain health.

Chemical Structure and Properties

Eicosanoyl-5-hydroxytryptamide is a amide compound. It consists of a serotonin molecule, which is a monoamine neurotransmitter, and an eicosanoic acid molecule, which is a long-chain fatty acid. The two molecules are connected by an amide bond. The chemical formula of EHT is C30H49N3O2.

Sources

EHT is naturally found in coffee. It is one of the many bioactive compounds present in coffee that contribute to its taste and potential health benefits. The concentration of EHT in coffee can vary depending on the type of coffee and the brewing method.

Potential Health Benefits

Research has suggested that EHT may have neuroprotective effects. It has been found to protect neurons from damage caused by beta-amyloid proteins, which are implicated in Alzheimer's disease. EHT may also promote brain health by enhancing the function of mitochondria, the energy-producing structures in cells.

Research and Clinical Trials

While the potential health benefits of EHT are promising, more research is needed to fully understand its effects and potential uses in medicine. As of now, most of the research on EHT has been conducted in laboratory settings, and clinical trials in humans are limited.

See Also

• Coffee and health
• Neuroprotection
• Serotonin
• Eicosanoic acid