Eletriptan hydrobromide
Eletriptan Hydrobromide is a medication used in the treatment of migraine headaches. It belongs to a class of drugs known as triptans, which are selective serotonin receptor agonists.
Pharmacology[edit | edit source]
Eletriptan hydrobromide works by stimulating serotonin (or 5-hydroxytryptamine) 5-HT1B and 5-HT1D receptors located on intracranial blood vessels and sensory nerves of the trigeminal system, which results in vasoconstriction and inhibition of pro-inflammatory neuropeptide release.
Medical Uses[edit | edit source]
Eletriptan hydrobromide is primarily used for the acute treatment of migraines with or without aura in adults. It is not intended for the prophylactic therapy of migraines or for use in the management of hemiplegic or basilar migraines.
Side Effects[edit | edit source]
Common side effects of eletriptan hydrobromide include dizziness, nausea, weakness, drowsiness, and pain or pressure sensations in the chest or throat. Serious side effects may include heart attack or stroke, particularly in patients with risk factors for these conditions.
Contraindications[edit | edit source]
Eletriptan hydrobromide is contraindicated in patients with a history of coronary artery disease, angina, or other significant underlying cardiovascular disease. It is also contraindicated in patients with uncontrolled hypertension or a history of hemiplegic or basilar migraine.
Drug Interactions[edit | edit source]
Eletriptan hydrobromide can interact with certain other medications, including monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors, which can increase the risk of serotonin syndrome.
See Also[edit | edit source]
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