Emedastine difumarate
Emedastine Difumarate is a second-generation antihistamine primarily used in the treatment of allergic conjunctivitis. It is marketed under the trade name Emadine.
Pharmacology[edit | edit source]
Emedastine difumarate is a relatively selective, H1 receptor antagonist, which inhibits the release of histamine from mast cells, thereby preventing the symptoms of allergic reactions. It does not have any significant anticholinergic effects.
Clinical Use[edit | edit source]
Emedastine difumarate is used in the form of eye drops to treat the symptoms of allergic conjunctivitis, such as itching, redness, and swelling. It is typically used twice daily, and its effects can be noticed within a few minutes of application.
Side Effects[edit | edit source]
The most common side effects of emedastine difumarate include headache, burning or stinging in the eyes, and blurred vision. Less common side effects can include dry eyes, eye pain, and sensitivity to light.
Interactions[edit | edit source]
Emedastine difumarate is not known to interact significantly with other drugs. However, it is always recommended to inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and dietary supplements.
Precautions[edit | edit source]
Emedastine difumarate should not be used by individuals who are allergic to it or any of its ingredients. It should be used with caution in individuals with narrow-angle glaucoma, and in those who wear contact lenses, as it may cause discoloration.
Pregnancy and Lactation[edit | edit source]
The safety of emedastine difumarate during pregnancy and lactation has not been established. Therefore, it should only be used if the potential benefits outweigh the potential risks.
References[edit | edit source]
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