Endogeny

Endogeny

Endogeny refers to the process or state of being generated or produced from within an organism, system, or process. In biological contexts, it often pertains to substances or phenomena that originate internally rather than from external sources. This concept is crucial in understanding various physiological and pathological processes in medical science.

Biological Context

In biology, endogeny is contrasted with exogeny, which involves external origins. Endogenous processes are integral to the normal functioning of organisms and can include the production of hormones, enzymes, and other biochemical substances.

Endogenous Substances

Endogenous substances are those that are synthesized within the body. Examples include:

• Hormones: Such as insulin, which is produced by the pancreas, and plays a critical role in regulating blood glucose levels.
• Neurotransmitters: Like dopamine and serotonin, which are synthesized in the brain and are essential for neural communication.
• Endogenous Antioxidants: Such as glutathione, which helps protect cells from oxidative stress.

Endogenous Processes

Endogenous processes are those that occur within an organism without external influence. These include:

• Endogenous Rhythms: Biological rhythms that are generated internally, such as the circadian rhythm, which regulates sleep-wake cycles.
• Endogenous Repair Mechanisms: Processes like DNA repair and tissue regeneration that occur naturally within the body.

Medical Implications

Understanding endogeny is vital in medicine, particularly in diagnosing and treating diseases that involve endogenous factors. For instance, disorders of endogenous hormone production, such as diabetes mellitus, require careful management of internal insulin levels.

Endogenous Diseases

Diseases can be classified based on whether they are caused by endogenous or exogenous factors. Endogenous diseases are those that arise from internal dysfunctions, such as:

• Autoimmune Diseases: Where the immune system mistakenly attacks the body's own cells.
• Genetic Disorders: Such as cystic fibrosis, which result from inherited genetic mutations.

Also see

• Exogeny
• Endocrinology
• Homeostasis
• Circadian rhythm
• Autoimmune disease

Resources

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Endogeny for any updates.

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