Enterobacteriales

From WikiMD's Food, Medicine & Wellness Encyclopedia

Enterobacteriales is an order of bacteria that belongs to the class Gammaproteobacteria within the phylum Proteobacteria. This order encompasses a wide variety of bacteria that are significant in both medical and environmental contexts. Members of the Enterobacteriales are Gram-negative, facultatively anaerobic, and rod-shaped. They are known for their ability to reduce nitrate to nitrite and for their diverse metabolic capabilities, which allow them to inhabit various niches, including soil, water, plants, and animals.

Characteristics[edit | edit source]

Enterobacteriales are characterized by their Gram-negative cell walls, which consist of a thin layer of peptidoglycan surrounded by an outer membrane containing lipopolysaccharides. This structure contributes to their pathogenicity in humans and animals. They are facultatively anaerobic, meaning they can grow in the presence or absence of oxygen, which further broadens their ecological niches. The ability to ferment sugars is a hallmark of the Enterobacteriales, with many species producing gas from glucose fermentation.

Classification[edit | edit source]

The order Enterobacteriales is divided into several families, with the Enterobacteriaceae being the most well-known and largest family. This family includes many genera that are important in human and veterinary medicine, such as Escherichia, Salmonella, Shigella, and Yersinia. These genera contain species that are causative agents of gastrointestinal diseases, urinary tract infections, and plague, among others.

Pathogenicity[edit | edit source]

Many Enterobacteriales are pathogenic to humans and animals, causing a range of diseases. For example, Escherichia coli is a common cause of foodborne illness and urinary tract infections. Salmonella spp. are responsible for salmonellosis, a significant cause of gastroenteritis worldwide. Shigella spp. cause shigellosis, a severe form of dysentery. Yersinia pestis, the causative agent of plague, is also a member of this order. The pathogenicity of these bacteria is often related to their ability to produce toxins, invade host tissues, and evade the host immune system.

Ecological and Industrial Significance[edit | edit source]

In addition to their medical importance, Enterobacteriales play significant roles in the environment and industry. Some members are involved in the nitrogen cycle, contributing to soil fertility. Others are used in the biotechnology and fermentation industries, for the production of vitamins, antibiotics, and other bioactive compounds.

Prevention and Treatment[edit | edit source]

The prevention of diseases caused by Enterobacteriales involves proper hygiene, safe food handling practices, and vaccination for certain diseases like typhoid fever. Treatment typically includes the administration of antibiotics, although the increasing prevalence of antibiotic-resistant strains poses a significant challenge to treatment.

Conclusion[edit | edit source]

Enterobacteriales are a diverse group of bacteria with significant impacts on human health, ecology, and industry. Their ability to inhabit various environments and cause a range of diseases makes them a subject of ongoing research, particularly in the fields of microbiology, infectious diseases, and antibiotic resistance.

Enterobacteriales Resources
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Contributors: Prab R. Tumpati, MD